Between the years of 1447 (Nicholas V) and 1572 (Pius V) Rome was transformed from a ruined Medieval city. The Vatican became the official home of the church and the world's largest bureaucracy, a spectacular new Basilica of St Peters took 100 years to build and Michelangelo changed the course of art history with his Sistine Chapel. So vast and expensive was this cultural explosion that a new fundraising initiative was launched: the sale of indulgences. The Renaissance Popes were statesmen, warriors, patrons of the arts - as well as churchmen. These were earthly times and the reputations of popes like Alexander VI, the infamous Borgia patriarch, and Julius 'II Terrible' for murder, poison, sodomy and simony vary only in degree. Meanwhile, the sin of heresy, which threatens the very core of the Catholic soul, was tirelessly targeted by two other lasting innovations of the period: the Inquisition and witch-hunts. Alexander VI, father of the ruthless Cesare and jezebel Lucrezia, is seen to this day as the embodiment of this iniquity. But Gerard Noel shows this is unjust, and based on false confessions and historical myth.